Conventional drug treatment for diabetes doesn't have a fantastic track record. Prescription medications have different side effects and are associated with severe health issues. Various kinds of studies have revealed that long-term use of some common diabetes drugs can increase the chance of cancer.
Oral Diabetes Medication May Raise Cancer Risk
An analysis of five-year data gathered in an ongoing 10-year study, conducted by Takeda Pharmaceuticals, showed a link between the typical anti-diabetes medication Actos and increased risk of bladder cancer.
Actos is an oral prescription medication that's used for treating type 2 diabetes mellitus. The generic name of the medication is pioglitazone. It belongs to this class of drug called peroxisome proliferator-activated receptor (PPAR) agonists.
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The observational cohort study was conducted on 193,000 diabetics connected with the Kaiser Permanente Northern California health plan. Greater episodes of bladder cancer were observed among patients that received pioglitazone for a minimum of two years, as compared to people on other drugs.
Also, the diabetics with the maximum exposure to the medication and people that have the greatest cumulative dose experienced a greater risk of bladder cancer.
A second study, conducted by Larry L. Hillblom Islet Research Centre in UCLA, associated a diabetes drug, sitagliptin with the heightened risk of pancreatic cancer and pancreatitis. Sitagliptin is used as a treatment for type 2 diabetes.
The analysis was conducted on 40 individual IAPP transgenic (HIP) rats. The researchers discovered that some rats had exceptionally high rates of cell production in the pancreatic tissues. Few rats developed a condition called ductal metaplasia and pancreatitis.
Some other studies conducted on animals have linked Victoza, another antipsychotic medication, with the greater risk of thyroid cancer.
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